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The incidence of respiratory disease in First Nations communities in Saskatchewan is significant. Since lung function is dependent on age, gender, height and ethnicity, a number of mathematical equations must be used to predict normal lung function values for individuals of different ethnic backgrounds. Dr. Mark Fenton is taking the first steps to determining such equations for Saskatchewan First Nations individuals.

Part of the assessment of respiratory disease involves a test called spirometry, where lung function is measured according to the amount and flow of air that can be inhaled and exhaled. Dr. Fenton is using spirometry to study Saskatchewan First Nation persons 18 years of age and older. The data he collects is being used to formulate equations that will predict normal lung function for people of First Nations descent. By establishing a benchmark, spirometry can then be used as a tool for assessing conditions such as asthma, pulmonary fibrosis, cystic fibrosis and COPD.

Dr. Fenton is comparing the resulting equations to those already established for Caucasians. By defining the differences in normal resting lung function between First Nations people and Caucasians, Dr. Fenton will identify major implications for the determination of normal and abnormal lung function in the clinical and/or research evaluation of First Nations individuals.

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