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In addition to carrying the “blueprint” for our bodies – every trait from eye colour to height – our genes also are constantly expressed to build and maintain our cells and body systems. Many diseases such as cancer occur when this gene expression goes awry, but discovering where and how genes are expressed can be a long and expensive process. The GEMS group is developing world-leading techniques at the Canadian Light Source synchrotron to easily follow gene expression in whole animals in real time. These techniques will allow the team to watch gene expression as a disease progresses – and be able to watch the action of therapeutic drugs to determine their effectiveness. While the initial focus will be on cancer, the GEMS techniques are expected to be applicable to a wide range of diseases.
Based at the U of S Academic Health Sciences Centre, GEMS draws expertise from the U of S College of Medicine and College of Arts and Science, including several Canada Research Chairs and prominent experts in synchrotron-based biomedical research.

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