Recipients

Vaccination is a key weapon in the fight against infectious diseases. One of the challenges in developing more effective vaccines is finding a better way to deliver antigens into the body to stimulate an immune system response. Researchers are constantly searching for safer, more effective methods. Although human adenovirus (HAdV) is believed by many to hold promise as a vector, or vehicle, for delivering foreign genes into humans and animals, it has a number of characteristics that limit its effectiveness. Dr. Enqi Du is trying to develop a nonhuman adenovirus (bovine adenovirus, or BAdV-3) that is modified to target specific cells (M cells in Peyer’s Patches) in the gastrointestinal tract. If successful, Dr. Du`s work may yield a safer and more effective means of administering oral vaccine to humans.

< Back to Search Results