Recipients

Vaccination is one way to reduce the incidence and consequences of numerous infectious diseases. However, delivery is one of the major barriers to developing more efficient vaccines. For example, human adenovirus vectors (HAdVs) are being developed to deliver vaccines in humans. However, problems arise in the delivery of the vaccines because the HAdVs are very unpredictable in nature and often transfer material to both targeted and non-targeted cells. The HAdVs’ unpredictability makes the vaccinations ineffective. Badea will look at ways to further develop non-human engineered targeted adenoviral vectors such as porcine adenovirus (PAdVs) to increase the effectiveness of vaccine delivery in humans. It is anticipated that this research will lead to more successful clinical trials in gene therapy in the future.

Badea’s research aligns well with Saskatchewan’s Health Research Strategy. It focuses on public health, including infectious diseases, water safety and food safety, a priority area within the Strategy.

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