Recipients
Chunfu Zheng
Vaccine and Infectious Disease Organization
University of Saskatchewan
Supervisor(s):
Sylvia Van Drunen Little-van den Hurk
DNA vaccination in animals and humans is a promising approach because of its safety and simplicity. However, to be effective, DNA vaccines need to enter the cell and nucleus of the host, which currently is a rather inefficient process. Drs. Zheng and van den Hurk will study two proteins of bovine herpes virus type 1, which are capable of entry into host cells or entry into the nucleus of the cells. If such critical traits of these proteins could be applied to DNA immunization, the efficacy this vaccination strategy would improve significantly. This project is relevant to both veterinary vaccinology and human medicine.
